Potential P-Glycoprotein-Mediated Drug-Drug Interactions of Antimalarial Agents in Caco-2 cells
نویسندگان
چکیده
منابع مشابه
Potential P-glycoprotein-mediated drug-drug interactions of antimalarial agents in Caco-2 cells.
Antimalarials are widely used in African and Southeast Asian countries, where they are combined with other drugs for the treatment of concurrent ailments. The potential for P-glycoprotein (P-gp)-mediated drug-drug interactions (DDIs) between antimalarials and P-gp substrates was examined using a Caco-2 cell-based model. Selected antimalarials were initially screened for their interaction with P...
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ژورنال
عنوان ژورنال: The American Journal of Tropical Medicine and Hygiene
سال: 2012
ISSN: 0002-9637,1476-1645
DOI: 10.4269/ajtmh.2012.11-0817